منابع مشابه
Targeting epidermal lipids for treatment of Mendelian disorders of cornification
BACKGROUND Inherited ichthyoses or Mendelian disorders of cornification (MeDOC) are clinically heterogeneous disorders with high unmet therapeutic needs, which are characterized by skin hyperkeratosis and scaling. Some MeDOC types are associated with defects of the epidermal lipid metabolism, resulting in perturbed barrier permeability and subsequent epidermal hyperplasia, hyperkeratosis and in...
متن کاملThematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis.
The permeability barrier is required for terrestrial life and is localized to the stratum corneum, where extracellular lipid membranes inhibit water movement. The lipids that constitute the extracellular matrix have a unique composition and are 50% ceramides, 25% cholesterol, and 15% free fatty acids. Essential fatty acid deficiency results in abnormalities in stratum corneum structure function...
متن کاملPriority Dropping for Scalable Video
For H.264/SVC, different layers or frames have different order of precedence according to their importance on video quality and the decoding process. Network should provide more protection for high priority layers or frames when SVC stream is transmitted over IP network. This paper proposes an active queue management algorithm based on priority dropping and PID algorithm, called PID_PD, which f...
متن کاملEffect of hormone replacement therapy on epidermal barrier lipids.
Current evidence of the effect of hormone replacement therapy (HRT) on skin lipids, of postmenopausal women is scanty and indirect. Here, we report the ultrastructural differences in epidermal lipids between postmenopausal subjects who were and were not on HRT and a comparison is made with younger subjects. Biopsies were obtained from arms and legs, in a blinded, no-treatment, study conducted o...
متن کاملThe Role of Epidermal Lipids in Cutaneous Permeability Barrier Homeostasis
The permeability barrier is required for terrestrial life and is localized to the stratum corneum, where extracellular lipid membranes inhibit water movement. The lipids that constitute the extracellular matrix have a unique composition and are 50% ceramides, 25% cholesterol, and 15% free fatty acids. Essential fatty acid deficiency results in abnormalities in stratum corneum structure function...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2003
ISSN: 0022-202X
DOI: 10.1046/j.1523-1747.2003.12383.x