Driving pressure-guided ventilation versus protective lung ventilation in ARDS patients: A prospective randomized controlled study

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Effect of driving pressure on mortality in ARDS patients during lung protective mechanical ventilation in two randomized controlled trials

BACKGROUND Driving pressure (ΔPrs) across the respiratory system is suggested as the strongest predictor of hospital mortality in patients with acute respiratory distress syndrome (ARDS). We wonder whether this result is related to the range of tidal volume (VT). Therefore, we investigated ΔPrs in two trials in which strict lung-protective mechanical ventilation was applied in ARDS. Our working...

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Prospective randomized trial comparing pressure-controlled ventilation and volume-controlled ventilation in ARDS. For the Spanish Lung Failure Collaborative Group.

STUDY OBJECTIVES To compare in-hospital mortality of patients with ARDS ventilated with either pressure-controlled ventilation (PCV) or volume-controlled ventilation (VCV) with a square-wave inspiratory flow. DESIGN : Multicenter and randomized trial. SETTING Twelve medical-surgical ICUs located in tertiary-care hospitals. PATIENTS Seventy-nine patients having ARDS, as defined by the Amer...

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PReVENT - protective ventilation in patients without ARDS at start of ventilation: study protocol for a randomized controlled trial

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Pressure-controlled ventilation and intrabronchial pressure during one-lung ventilation.

BACKGROUND Pressure-controlled ventilation (PCV) has been suggested to reduce peak airway pressure (P(peak)) and intrapulmonary shunt during one-lung ventilation (OLV) when compared with volume-controlled ventilation (VCV). At the same tidal volume (V(T)), the apparent difference in P(peak) is mainly related to the presence of a double-lumen tracheal tube. We tested the hypothesis that the decr...

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ژورنال

عنوان ژورنال: Egyptian Journal of Anaesthesia

سال: 2021

ISSN: 1110-1849

DOI: 10.1080/11101849.2021.1930401