منابع مشابه
Long-term cognitive impairment after critical illness.
BACKGROUND Survivors of critical illness often have a prolonged and disabling form of cognitive impairment that remains inadequately characterized. METHODS We enrolled adults with respiratory failure or shock in the medical or surgical intensive care unit (ICU), evaluated them for in-hospital delirium, and assessed global cognition and executive function 3 and 12 months after discharge with t...
متن کاملLong-term neurocognitive function after critical illness.
BACKGROUND Until relatively recently, critical care practitioners have focused on the survival of their patients and not on long-term outcomes. The incidence of chronic neurocognitive dysfunction has been underestimated and underreported, and only recently has it been studied in critically ill patients. However, neurocognitive outcomes have been the subject of extensive investigation in other m...
متن کاملCirculating MicroRNA-223 Serum Levels Do Not Predict Sepsis or Survival in Patients with Critical Illness
BACKGROUND AND AIMS Dysregulation of miR-223 was recently linked to various diseases associated with systemic inflammatory responses such as type 2 diabetes, cancer, and bacterial infections. However, contradictory results are available on potential alterations of miR-223 serum levels during sepsis. We thus aimed to evaluate the diagnostic and prognostic value of miR-223 serum concentrations in...
متن کاملCommentary: driving and psychiatric illness.
The article by Snyder and Bloom highlights the importance of physicians’ actively participating in the legislative process when medicolegal issues are involved. The specific forensic questions addressed by the authors focus on physician reporting of potentially impaired drivers—a problem that has been precipitated by the complexities involved in determining fitness to drive in the elderly. It i...
متن کاملDeficient mitochondrial biogenesis in critical illness: cause, effect, or epiphenomenon?
Recent studies indicate that mitochondrial dysfunction plays a role in the pathogenesis of a number of disease states. The importance of these organelles in shock and multiple organ dysfunction is of particular interest to those caring for the critically ill. Mitochondria have their own unique DNA (mtDNA) that encodes 13 essential subunits of electron transport chain enzymes, two ribosomal RNAs...
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ژورنال
عنوان ژورنال: Journal of the Intensive Care Society
سال: 2015
ISSN: 1751-1437
DOI: 10.1177/1751143714564817