Doxycycline Increases Absence-like Epileptic Seizures in WAG/Rij Rats
نویسندگان
چکیده
منابع مشابه
Models of epileptic seizures in immature rats.
Models of basic types of epileptic seizures are elaborated not only in adult but also in immature rodents. It is important because at least half of human epilepsies starts during infancy and childhood. This paper presents a review of chemically and electrically induced models of generalized convulsive and nonconvulsive (absence) seizures as well as models of partial simple (neocortical) and com...
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s | 23 investigate the efficacy of ETX treatment on absence seizures and its effect on potentially observable cardiovascular changes in genetic absence epileptic WAG/Rij rats. Method: We divided 2-month-old Wistar and WAG/Rij rats into two groups (n=16): Control and ETX groups. The ETX groups were treated with ETX (orally, 300 mg/kg/day) for 3 months. Control groups received physiological salin...
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Electrophysiological experiments have long revealed the existence of two-way transitions between absence and tonic-clonic epileptic seizures in the cerebral cortex. Based on a modified spatially-extended Taylor &Baier neural field model, we here propose a computational framework to mathematically describe the transition dynamics between these epileptic seizures. We first demonstrate the existen...
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PURPOSE Cardiac dysfunction is one of the possible causes of sudden unexpected death in epilepsy (SUDEP). Therefore, the objective of this study was to evaluate cardiac and electrocardiographic parameters in rats with audiogenic epileptic seizures (WAR--Wistar audiogenic rats). METHODS In vivo arterial pressure, heart rate (HR), autonomic tone and electrocardiography (ECG) were measured in aw...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2011
ISSN: 1662-453X
DOI: 10.3389/conf.fnins.2011.84.00163