Douglas Graham Altman

Understanding Bland Altman analysis

In a contemporary clinical laboratory it is very common to have to assess the agreement between two quantitative methods of measurement. The correct statistical approach to assess this degree of agreement is not obvious. Correlation and regression studies are frequently proposed. However, correlation studies the relationship between one variable and another, not the differences, and it is not r...

Reply to Collins and Altman.

We are pleased that EuroSCORE II [1] continues to generate interest and are happy to respond to concerns about its development and evaluation [2]. We find very little to disagree with in the points raised by Collins and Altman [3], but are not convinced that their suggested alternative analysis would have resulted in materially different results. Our approach to the analysis was traditional (sp...

Graham Lusk *

Validating the Bland-Altman Method of Agreement

Bland-Altman’s analysis and plot are the most common methods used to assess the relative agreement between two analytical methods that measure the continuous variables measured on the same scale. Many agreement studies have shown that using the t-test or the Pearson’s product-moment correlation is flawed when measuring the agreement or detecting the bias. Bland-Altman proposed graphical techniq...

Publications for Graham Mann

De Paoli-Iseppi, R., Johansson, P., Menzies, A., Dias, K., Pupo, G., Kakavand, H., Wilmott, J., Mann, G., Hayward, N., Dinger, M., Long, G., Scolyer, R. (2016). Comparison of whole-exome sequencing of matched fresh and formalin fixed paraffin embedded melanoma tumours: implications for clinical decision making. Pathology, 48(3), 261-266. ...