Double vs. single cord blood transplantation in adolescent and adult hematological malignancies with heavier body weight (≥50 kg)
نویسندگان
چکیده
منابع مشابه
Phase II study of intrabone single unit cord blood transplantation for hematological malignancies
The outcomes of cord blood transplantation with non-irradiated reduced-intensity conditioning for hematological malignancies need to be improved because of graft failure and delayed engraftment. Intrabone infusion of cord blood cells has the potential to resolve the problems. In this phase II study, 21 adult patients with hematological malignancy received intrabone transplantation of serologica...
متن کاملSingle-institute comparative analysis of unrelated bone marrow transplantation and cord blood transplantation for adult patients with hematologic malignancies.
Unrelated cord blood transplantation (CBT) has now become more common, but as yet there have been only a few reports on its outcome compared with bone marrow transplantation (BMT), especially for adults. We studied the clinical outcomes of 113 adult patients with hematologic malignancies who received unrelated BM transplants (n = 45) or unrelated CB transplants (n = 68). We analyzed the hematop...
متن کاملClinical outcomes of unrelated donor umbilical cord blood transplantation for 30 adults with hematological malignancies.
BACKGROUND Umbilical cord blood transplantation (CBT) has increasingly been used as a therapeutic option for adult patients for whom allogeneic stem-cell transplantation is not indicated, due to the availability of cord blood. However, myeloablative conditioning regimens are associated with significant mortality, and high relapse rates in reduced-intensity regimens may result in a poor rate of ...
متن کاملSuccessful engraftment after reduced-intensity umbilical cord blood transplantation for adult patients with advanced hematological diseases.
PURPOSE The purpose of this research was to evaluate the feasibility of reduced-intensity unrelated cord-blood transplantation (RI-UCBT) in adult patients with advanced hematological diseases. EXPERIMENTAL DESIGN Thirty patients (median age, 58.5 years; range, 20-70 years) with advanced hematological diseases underwent RI-UCBT at Toranomon Hospital between September 2002 and August 2003. Prep...
متن کاملSalvaged single-unit cord blood transplantation for 26 patients with hematologic malignancies not in remission.
Treatments for patients with hematologic malignancies not in remission are limited, but a few clinical studies have investigated the effects of salvaged unrelated cord blood transplantation (CBT). We retrospectively studied 19 patients with acute leukemia, 5 with myelodysplastic syndrome (MDS with refractory anemia with excess blasts [RAEB]), and 2 with non-Hodgkin's lymphoma who received 1 CBT...
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ژورنال
عنوان ژورنال: Hematology
سال: 2017
ISSN: 1607-8454
DOI: 10.1080/10245332.2017.1361078