Double-blind Trial of Propranolol (Inderal) in Angina of Effort

Double-blind Trial of Propranolol (inderal) in Angina of Effort.

Blockade of adrenergic beta-receptors has a possible application in the management of angina of effort, presumably through reduction of exercise-induced tachycardia and thereby of total cardiac work. A clinical trial with pronethalol has shown encouraging results (Alleyne et al., 1963). Its further use has, however, been limited partly by frequent central-nervous-system side-effects and partly ...

Double-blind Trial of Propranolol (inderal) in Angina Pectoris.

A double-blind randomized trial of propranolol and verapamil in the treatment of effort angina.

In 18 patients with stable effort angina, verapamil, 80 mg four times daily, was compared with propranolol, 80 mg four times daily, in a double-blind, placebo-controlled trial to assess the effects on anginal threshold, exercise capacity and left ventricular function measured by gated equilibrium blood pool scanning. Both propranolol and verapamil improved exercise capacity (placebo 424 +/- 135...

Effect of Propranolol (inderal) in Angina Pectoris: Preliminary Report.

Comparison of Propranolol and Inderal L.A. in Patients with Angina

TWELVE patients with moderately severe angina pectoris completed a double blind cross-over comparison of conventional propranolol (40 mg q.i.d.) and Inderal L.A. (160 mg once daily) with regard to therapeutic effectiveness, blood levels, compliance and patient acceptability.Exercise tolerance was assessed using standardised treadmill testing at 1, 2, 4, 8, 12 and 24 hours after the morning dose...