Dosimetric verification of clinical radiotherapy treatment planning system

Background/Aim. In the past two decades, we have witnessed emergence of new radiation therapy techniques, radiotherapy treatment planning system (TPS) with calculating algorithms for dosage calculation in a patient, units multislice computed tomography (CT) and image-guided delivery. The aim study was investigating significant difference dosimetric TPS relation to values obtained by measuring on linear accelerator (LINAC), accuracy between Analytical Anisotropic Algorithm (AAA) Acuros XB various tissues photon beam energies. Methods. For End-to-End test used hetero-geneous phantom CIRS Thorax002LFC, which anatomically represents human torso set inserts known as relative electron densities (RED) obtaining CT calibration curve, comparable ?reference? 062M phantom. AAA 6 MV 16 beams Varian Eclipse 13.6, four 3D conformal (3DCRT), one intensity modulated (IMRT) volumetric arc (VMAT) plans were made. Measurements absolute dose Thorax phantom, PTW-Semiflex ionization chamber, carried out three Varian-DHX LINACs. Results. measured conversion curves bone area 3%. 476 measurements, calculated 3?6%, found 30 (6.3%) cases. According regression analysis, standardized Beta coefficient errors, vs. MV, 0.337 (33.7%, p < 0.001). Mean errors XB, using Mann-Whitney test, bones 1.56% 2.64%, respectively (p = 0.004). Conclusion. Thorax002LFC proved delivered patient LINAC. There energies (higher are MV). A statistically minor error bone.