Dose-response estimation by smoothing and area under the curve

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Dose-response estimation by smoothing and area under the curve

Many current dose-response methods assume a parametric shape of some form and do not accommodate comparisons between methods. Motivated by a need to be able to compare dose-response curves without assuming a parametric shape to the dose-response curve, we applied our technique to model them by non-parametric smoothing methods and also estimate area under the curves. Given that we do not know th...

متن کامل

Dose estimation with the calibration of dose-response curve of micronucleus in human peripheral lymphocytes induced by 50MeV proton beams

Background: The purpose of this paper is to establish an easy and reliable biodosimeter protocol to evaluate the biological effects of proton beams. Materials and Methods: Human peripheral blood lymphocytes were irradiated using proton beams (LET: 34.6 keV μm−1), and the chromosome aberrations induced were analyzed using cytokinesis-blocked (CB) micronucleus (MN) assay. To determine th...

متن کامل

Risk Estimation by Maximizing the Area under ROC Curve

Risks exist in many different domains; medical diagnoses, financial markets, fraud detection and insurance policies are some examples. Various risk measures and risk estimation systems have hitherto been proposed and this paper suggests a new risk estimation method. Risk estimation by maximizing the area under a receiver operating characteristics (ROC) curve (REMARC) defines risk estimation as ...

متن کامل

Estimation of the area under the ROC curve.

The area under the receiver operating characteristic curve is frequently used as a measure for the effectiveness of diagnostic markers. In this paper we discuss and compare estimation procedures for this area. These are based on (i) the Mann-Whitney statistic; (ii) kernel smoothing; (iii) normal assumptions; (iv) empirical transformations to normality. These are compared in terms of bias and ro...

متن کامل

dose estimation with the calibration of dose-response curve of micronucleus in human peripheral lymphocytes induced by 50mev proton beams

background: the purpose of this paper is to establish an easy and reliable biodosimeter protocol to evaluate the biological effects of proton beams. materials and methods: human peripheral blood lymphocytes were irradiated using proton beams (let: 34.6 kev μm−1), and the chromosome aberrations induced were analyzed using cytokinesis-blocked (cb) micronucleus (mn) assay. to determine the efficie...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Medical Statistics and Informatics

سال: 2016

ISSN: 2053-7662

DOI: 10.7243/2053-7662-4-7