Dose received by external genital organs during preoperative radiotherapy for rectal cancer patients
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چکیده
منابع مشابه
Developing the Adult Male ICRP Phantom and Evaluation the Absorbed Dose Received By Critical Organs in Head and Neck Region during the Radiotherapy of Eye Cancer
Introduction Accurate estimation of the absorbed dose in radiosensitive organs, located away from the target volume during radiotherapy, is one of the main reasons for the development of reference phantoms. The International Commission on Radiological Protection (ICRP) reference phantoms can provide a more realistic view of the human anatomy in comparison with the previously used mathematical p...
متن کاملPhase I study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer.
3552 Background: Capecitabine has the potential to replace 5-FU as standard agent in combination with radiotherapy in rectal cancer. Cetuximab is a monoclonal antibody directed against the epidermal growth factor receptor. Both agents are active in the treatment of colorectal cancer and have demonstrated radiosensitising properties. The aim of this study was to assess the feasibility of combini...
متن کاملPredictive factors of tumor shrinkage and histological regression in patients who received preoperative radiotherapy for rectal cancer.
OBJECTIVE In order to determine the reliable predictors of response to radiotherapy for rectal cancer, we assessed apoptosis, p53 and p21 in biopsy specimens collected before treatment, and investigated the relationships to the histological effect of irradiation and the degree of tumor shrinkage. METHODS Ninety-three patients with advanced rectal adenocarcinoma were treated with preoperative ...
متن کاملAn Update on Preoperative Radiotherapy for Locally Advanced Rectal Cancer
Even in patients undergoing an optimal surgical technique (e.g., total mesorectal excision), radiotherapy provides a significant benefit in the local control of rectal cancer. Compared with postoperative treatment, chemoradiotherapy given preoperatively has been shown to decrease local recurrence rates and toxicity. Additionally, preoperative chemoradiotherapy permits the early identification o...
متن کاملPreoperative radiotherapy for resectable rectal cancer: A meta-analysis.
CONTEXT The benefit of adjuvant radiotherapy for resectable rectal cancer has been extensively studied, but data on survival are still equivocal despite a reduction in the rate of local recurrence. OBJECTIVE To assess the effectiveness of preoperative radiotherapy followed by surgery in the reduction of overall and cancer-related mortality and in the prevention of local recurrence and distant...
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ژورنال
عنوان ژورنال: Journal of Radiation and Cancer Research
سال: 2020
ISSN: 2588-9273
DOI: 10.4103/jrcr.jrcr_15_20