Dopamine-Induced Gangrene

Cryoglobulinaemia induced digital gangrene in a case of hepatitis C.

DESCRIPTION A 65-year-oldwoman presentedwith severe pain in the fingers of both hands (figure 1). The patient was diagnosed with hepatitis C virus (HCV), following blood transfusion 30 years ago, and had developed the associated pathologies of cirrhosis and cryoglobulinaemia. Over the past 7 years, she had required multiple hospital admissions to treat associated complications. These consisted ...

Gangrene induced by methysergide and ergotamine. A case report.

Outbreaks of ergot poisoning (St Anthony’s fire) have occurred in Europe for centuries, the most recent being in 1 953. Ergot is the product of a parasitic fungus infecting grain, in particular rye, and has been recognised as the cause of St Anthony’s fire since the Middle Ages. However, it was not until 1920 that the amino-acid alkaloid, ergotamine, was isolated by Stoll. Ergotamine can reprod...

Dopamine - induced dissociation of BOLD -

Fournier’s gangrene

An 80-year-old diabetic man (type 2) with detrusor underactivity treated by long-term urethral catheterization attended the emergency department with a 4-day history of scrotal swelling and pain and an associated offensive discharge. Physical examination revealed a grossly swollen right hemi-scrotum with gangrene. Crepitus and erythema were noted over the discolored area, extending into the rig...

Breast Gangrene

BACKGROUND Breast gangrene is rare in surgical practice. Gangrene of breast can be idiopathic or secondary to some causative factor. Antibiotics and debridement are used for management. Acute inflammatory infiltrate, severe necrosis of breast tissue, necrotizing arteritis, and venous thrombosis is observed on histopathology. The aim of was to study patients who had breast gangrene. METHODS A ...