Don't live in a town where there are no doctors: toxic epidermal necrolysis initially misdiagnosed as oral thrush
نویسندگان
چکیده
منابع مشابه
[Toxic epidermal necrolysis].
Toxic epidermal necrolysis is a potentially fatal dermatological disease. Large bullae covering extensive areas of the body cause continuous exfoliation of skin, which requires immediate medical attention. Intraoral manifestations may precede cutaneous lesions. Two cases with different treatment protocols are presented.
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Figure 1. Generalized epidermolysis on anterior and posterior torso with crusty erosions on oral mucosa. DESCRIPTION A 33-year-old woman presents with diffuse rash 3 weeks after completing a course of Bactrim for a urinary tract infection. Erythematous maculopapular rash is evident on the trunk and extremities with painful, epidermal sloughing on the back leaving a moist, denuded dermis. Note t...
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This syndrome was first described by Lyell (1956) in this country and by Lang and Walker (1956) in South Africa and has since been reported with increasing frequency. Beare (1962), in a comprehensive review, collected 35 cases from the published reports and described 10 further cases that he had observed personally. He suggests that it is unlikely that the syndrome could have been seen in the U...
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Toxic epidermal necrolysis syndrome (TENS) is a rare, life-threatening medical emergency typically associated with recent drug exposure. Although several theories exist, recent insight has implicated the innate immune system as a significant contributor to the initiation and propagation of this devastating reaction. Standard therapies including transfer to specialized burn units, nutritional su...
متن کاملThalidomide in toxic epidermal necrolysis.
Sir—The report of unexplained deaths associated with thalidomide therapy for toxic epidermal necrolysis by Pierre Wolkenstein and colleagues (Nov 14, p 1586), points to the need for a more complete understanding of the putative mechanism(s) of action of this drug. This issue is lent further urgency by the recent licensure of thalidomide by the US Food and Drug Administration for the treatment o...
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ژورنال
عنوان ژورنال: Case Reports
سال: 2009
ISSN: 1757-790X
DOI: 10.1136/bcr.10.2009.2392