منابع مشابه
Climatic regulation of the neurotoxin domoic acid.
Domoic acid is a potent neurotoxin produced by certain marine microalgae that can accumulate in the foodweb, posing a health threat to human seafood consumers and wildlife in coastal regions worldwide. Evidence of climatic regulation of domoic acid in shellfish over the past 20 y in the Northern California Current regime is shown. The timing of elevated domoic acid is strongly related to warm p...
متن کاملRapid downward transport of the neurotoxin domoic acid in coastal waters
Toxic phytoplankton blooms threaten coastlines worldwide by diminishing beach quality and adversely affecting marine ecosystems and human health1,2. The common diatom genus Pseudo-nitzschia consists of several species known to produce the neurotoxin domoic acid3. Recent studies suggest that algal blooms dominated by Pseudo-nitzschia are increasing in frequency and duration owing to changes in c...
متن کاملDomoic Acid Epileptic Disease
Domoic acid epileptic disease is characterized by spontaneous recurrent seizures weeks to months after domoic acid exposure. The potential for this disease was first recognized in a human case study of temporal lobe epilepsy after the 1987 amnesic shellfish-poisoning event in Quebec, and was characterized as a chronic epileptic syndrome in California sea lions through investigation of a series ...
متن کاملControls on Domoic Acid Production
Nitzschia pungens f. multiseries (clone NPARL) was grown in nonaxenic batch culture under a range of growth conditions. Domoic acid (DA) was not detected during exponential growth, but production promptly started at a rate of approximately 1 pg DA'cell1 ·d1 atthe onset of the stationary phase, in this case induced by silicate limitation. Cellular DA reached a maximum of 7 pg-cell": thereafter, ...
متن کاملDomoic acid: a fascinating marine toxin.
There are indications that toxic algal blooms are increasing because of pollution of coastal waters and worldwide shipping. This mini-review deals with the marine biotoxin domoic acid, also known as amnesic shellfish poison, and its main producing pennate diatom genus Pseudo-nitzschia (Bacillariophyceae). Besides contamination of seafood, these organisms have also been involved in human and mar...
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ژورنال
عنوان ژورنال: NeuroToxicology
سال: 2010
ISSN: 0161-813X
DOI: 10.1016/j.neuro.2010.05.003