Dominantly Inherited Peripheral Neuropathies

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Inherited peripheral neuropathies.

Mutations in genes expressed in Schwann cells and the axons they ensheathe cause the hereditary motor and sensory neuropathies, also known as Charcot-Marie-Tooth disease (CMT). More than 40 different genes have been shown to cause inherited neuropathies; chromosomal localizations of many other distinct inherited neuropathies have been mapped, and new genetic causes for inherited neuropathies co...

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Inherited neuropathies.

OPINION STATEMENT Inherited peripheral neuropathies are among the most common hereditary diseases of the nervous system. Charcot-Marie-Tooth (CMT) disease, also known from previous classifications as hereditary motor and sensory neuropathy (HMSN), is certainly the most common inherited neuropathy. In the past several years, various treatments for CMT have been proposed, although specific therap...

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ژورنال

عنوان ژورنال: Journal of Neuropathology & Experimental Neurology

سال: 2003

ISSN: 0022-3069,1554-6578

DOI: 10.1093/jnen/62.7.699