Does Prohibitin Expression Regulate Sperm Mitochondrial Membrane Potential, Sperm Motility, and Male Fertility?
نویسندگان
چکیده
منابع مشابه
The effect of aminoguanidine on sperm motility and mitochondrial membrane potential in varicocelized rats
Objective(s): Increased levels of nitric oxide (NO) in the testicular veins of people suffering from varicocele have already been reported. However, the role of NO-synthase (NOS) isozymes and their inhibitors have not been extensively studied. We aimed to evaluate the inhibitory effects of aminoguanidine (AG), on sperm motility, vitality, and mitochondrial membrane potential (MMP) in varicoceli...
متن کاملPlasma membrane Ca2+ ATPase 4 is required for sperm motility and male fertility.
Calcium and Ca(2+)-dependent signals play a crucial role in sperm motility and mammalian fertilization, but the molecules and mechanisms underlying these Ca(2+)-dependent pathways are incompletely understood. Here we show that homozygous male mice with a targeted gene deletion of isoform 4 of the plasma membrane calcium/calmodulin-dependent calcium ATPase (PMCA), which is highly enriched in the...
متن کاملPlasma Membrane Ca ATPase 4 Is Required for Sperm Motility and Male Fertility*
From the ‡Institute for Clinical Biochemistry and Pathobiochemistry, University of Wuerzburg, Josef-Schneider-Strasse 2, D-97080 Wuerzburg, Germany, the Biochemical Research and Study Center, University of Latvia, Ratsupites iela 1, Riga, LV-1067, Latvia, the **Department of Obstetrics and Gynecology, University of Wuerzburg, Josef-Schneider-Str. 2, D-97080 Wuerzburg, Germany, the ‡‡FMP, Krahme...
متن کاملthe effect of aminoguanidine on sperm motility and mitochondrial membrane potential in varicocelized rats
objective(s): increased levels of nitric oxide (no) in the testicular veins of people suffering from varicocele have already been reported. however, the role of no-synthase (nos) isozymes and their inhibitors have not been extensively studied. we aimed to evaluate the inhibitory effects of aminoguanidine (ag), on sperm motility, vitality, and mitochondrial membrane potential (mmp) in varicoceli...
متن کاملSperm motility index and it’s relation to sperm concentration in subjects with impaired fertility potential
A cross sectional study of sperm motility index (SMI) in normozoospermic and oligoasthenoteratozoospermic males was undertaken to find correlation between sperm concentration and SMI. Two-hundred subjects with impaired fertility potential were screened for the routine seminogram parameters along with SMI using sperm quality analyzer (SQA IIB) to find out the SMI in the population of central Ind...
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ژورنال
عنوان ژورنال: Antioxidants & Redox Signaling
سال: 2012
ISSN: 1523-0864,1557-7716
DOI: 10.1089/ars.2012.4514