Does metformin improve in vitro maturation and ultrastructure of oocytes retrieved from estradiol valerate polycystic ovary syndrome-induced rats
نویسندگان
چکیده
منابع مشابه
Does metformin improve in vitro maturation and ultrastructure of oocytes retrieved from estradiol valerate polycystic ovary syndrome-induced rats
BACKGROUND Metformin decreases polycystic ovary syndrome (PCOS) symptoms, induces ovulation, and may improve developmental competence of in vitro oocyte maturation. This study was designed to define the effects of metformin on the characteristics of in vitro oocyte maturation in estradiol valerate (EV) PCOS-induced rats. METHODS Forty-five adult female Sprague-Dawley rats were randomly divide...
متن کاملChanges of The Uterine Tissue in Rats With Polycystic Ovary Syndrome Induced by Estradiol Valerate
Objective : Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. Reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. In this study, the effect of PCOS induction was studied using estradiol valerate. MaterialsAndMethods Adult ...
متن کاملHistochemical study of estradiol valerate-induced polycystic ovary syndrome in the rat
For the present study, and follow-up of histochemical changes in estradiol valerate-induced polycysticovary syndrome (PCOS), 48 virgin 90-day-old female rats were used. The rats were divided into thetreatment and control groups. For each rat of the treatment group, 4 mg estradiol valerate was injectedthrough intramuscular route for the induction of PCOS. The control group was taken the same amo...
متن کاملchanges of the uterine tissue in rats with polycystic ovary syndrome induced by estradiol valerate
objective: : polycystic ovary syndrome (pcos) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. in this study, the effect of pcos induction was studied using estradiol valerate. materials and methods: ad...
متن کاملChanges of The Uterine Tissue in Rats with Polycystic Ovary Syndrome Induced by Estradiol Valerate
BACKGROUND Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. Reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. In this study, we assess the effect of PCOS induction by estradiol valerate (EV) in a rat model. MATERIALS ...
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ژورنال
عنوان ژورنال: Journal of Ovarian Research
سال: 2015
ISSN: 1757-2215
DOI: 10.1186/s13048-015-0203-x