Does Inflammation after Stroke Affect the Developing Brain Differently than Adult Brain?

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Does inflammation after stroke affect the developing brain differently than adult brain?

The immature brain is prone to hypoxic-ischemic encephalopathy and stroke. The incidence of arterial stroke in newborns is similar to that in the elderly. However, the pathogenesis of ischemic brain injury is profoundly affected by age at the time of the insult. Necrosis is a dominant type of neuronal cell death in adult brain, whereas widespread neuronal apoptosis is unique for the early postn...

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ژورنال

عنوان ژورنال: Developmental Neuroscience

سال: 2009

ISSN: 1421-9859,0378-5866

DOI: 10.1159/000232556