Does cannabis use predispose to chronic airflow obstruction?

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Does cannabis use predispose to chronic airflow obstruction?

C annabis (derived from the ubiquitous plant, Cannabis sativa, and also known as marijuana) is the most widely used illicit drug worldwide, as well as the second most commonly smoked substance after tobacco, with an estimated 166 million users (3.9% of 15–64 yr olds) [1]. Its wide popularity is due to the euphoric effects of its major psychoactive ingredient, D-tetrahydrocannabinol (THC). Since...

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Aspects of chronic airflow obstruction.

This report questions several commonly used definitions and commonly accepted concepts. It suggest that the term, "chronic airflow obstructions," should replace the terms, "chronic obstructive pulmonary disease," "chronic obstructive lung disease," or "chronic airway obstruction," because it is flow that is obstructed. It is suggested the term, "chronic mucous hypersecretion," be used, rather t...

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Smoking, asthma, chronic airflow obstruction and COPD.

Cigarette smoking is the most prevalent risk factor for the development of adult-onset respiratory diseases associated with airflow obstruction, namely emphysema and chronic bronchitis, commonly called chronic obstructive pulmonary disease (COPD). Regrettably, childhood asthma does not reduce the likelihood of initiation of smoking [1] but it is not fully clear how smoking impacts pre-existing ...

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Moderately severe chronic airflow obstruction. Can corticosteroids slow down obstruction?

In a former study in patients with severe chronic airflow obstruction (CAO), (forced expiratory volume in one second (FEV1) ranging from 350-910 ml), we concluded that daily oral corticosteroids might slow down the progression of disease. The results of the present long-term (14-20 yr) study on 139 non-allergic patients with less severe CAO (FEV1 greater than or equal to 1200 ml, FEV1 as a perc...

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The natural history of chronic airflow obstruction.

A prospective epidemiological study of the early stages of the development of chronic obstructive pulmonary disease was performed on London working men. The findings showed that forced expiratory volume in one second (FEV1) falls gradually over a lifetime, but in most non-smokers and many smokers clinically significant airflow obstruction never develops. In susceptible people, however, smoking ...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2009

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00109309