منابع مشابه
The Journal of Nutrition Symposium: Dietary PUFA and the Aging Brain—Food for Thought Docosahexaenoic Acid and the Aging Brain
The dietary essential PUFA docosahexaenoic acid [DHA; 22:6(n-3)] is a critical contributor to cell structure and function in the nervous system, and deficits in DHA abundance are associated with cognitive decline during aging and in neurodegenerative disease. Recent studies underscore the importance of DHA-derived neuroprotectin D1 (NPD1) in the homeostatic regulation of brain cell survival and...
متن کاملCoordination of Gene Expression of Arachidonic and Docosahexaenoic Acid Cascade Enzymes during Human Brain Development and Aging
BACKGROUND The polyunsaturated arachidonic and docosahexaenoic acids (AA and DHA) participate in cell membrane synthesis during neurodevelopment, neuroplasticity, and neurotransmission throughout life. Each is metabolized via coupled enzymatic reactions within separate but interacting metabolic cascades. HYPOTHESIS AA and DHA pathway genes are coordinately expressed and underlie cascade inter...
متن کاملMaternal docosahexaenoic acid-enriched diet prevents neonatal brain injury.
Hypoxic-ischemic encephalopathy due to neonatal asphyxia is one of the most important causes of delayed neurological development. Prolonged neuronal apoptosis plays an important role in the processes contributing to neuronal degeneration. Docosahexaenoic acid (DHA), a major component of brain membrane phospholipids, prevents neuronal cell apoptosis and plays an important role as an anti-oxidant...
متن کاملDocosahexaenoic acid and the preterm infant
Docosahexaenoic acid (DHA) is a long chain poly-unsaturated fatty acid (LCPUFA) that has a role in the cognitive and visual development, as well as in the immune function of newborns. Premature infants are typically deficient in DHA for several reasons, to include fetal accretion of DHA that typically occurs during the third trimester. These premature infants are reliant on enteral sources of D...
متن کاملDietary supplementation with the omega-3 fatty acid docosahexaenoic acid in traumatic brain injury.
BACKGROUND Although various strategies for prevention of brain disease have been implemented, no substance has been found to be advantageous for prophylaxis against brain injury. OBJECTIVE While previous work in our laboratory and others have shown positive effects using the omega-3 fatty acid docosahexaenoic acid (DHA) in post-injury treatment following traumatic and ischemic insults, we wis...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2008
ISSN: 0022-3166,1541-6100
DOI: 10.3945/jn.108.096016