Docosahexaenoic acid ameliorates aluminum induced biochemical and morphological alteration in rat cerebellum

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Docosahexaenoic acid ameliorates aluminum induced biochemical and morphological alteration in rat cerebellum

BACKGROUND The omega-3 polyunsaturated fatty acids (PUFA), docosahexaenoic acid (DHA) have well-characterized effects on inflammation and oxidative stress and may have neuroprotective effects in a number of neurodegenerative conditions including AD. Brain tissue contains large amounts of polyunsaturated fatty acids, which are particularly vulnerable to free radical injury. PURPOSE The present...

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Docosahexaenoic Acid Reverses Aluminium Induced Alteration in Vitamins and Lipid Profiles in Rat Serum

Aluminium (Al) is the third most widespread metal in the environment. It is known to be toxic for human and animals. We have studied the effect of simultaneous oral treatment of docosahexaenoic acid on aluminum induced changes in serum lipid profile and vitamins. A total of twenty four male albino rats were taken and divided in to four groups (N=6). First control group was treated with normal s...

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Riluzole Ameliorates Harmaline-Induced Tremor in Rat

Introduction: Excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. We hypothesized that antiglutamatergic agents would suppress harmaline tremor. From this point of view, the aim of current study was to investigate the effects of riluzole on harmaline-induced tremor in rat. Material and Methods: Four groups of Wistar rats weighing 80–100 g were injected with harmaline...

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riluzole ameliorates harmaline-induced tremor in rat

introduction: excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. we hypothesized that antiglutamatergic agents would suppress harmaline tremor. from this point of view, the aim of current study was to investigate the effects of riluzole on harmaline-induced tremor in rat. material and methods: four groups of wistar rats weighing 80–100 g were injected with harmaline...

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Gallic Acid Ameliorates Bisphenol A-Induced Toxicity in Wistar Rats

Background: Bisphenol A (BPA) has received attention in environmental and toxicological research due to its widespread effects in biological systems. While several anti-oxidants have been used in ameliorating BPA-induced toxicities in experimental animals, there is the scarcity of research information on the use of Gallic acid (GA) in protecting against BPA-induced toxicity. This study investig...

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ژورنال

عنوان ژورنال: Annals of Neurosciences

سال: 2014

ISSN: 0972-7531,0976-3260

DOI: 10.5214/ans.0972.7531.210103