Do Low Molecular Weight Agents Cause More Severe Asthma than High Molecular Weight Agents?
نویسندگان
چکیده
منابع مشابه
Do Low Molecular Weight Agents Cause More Severe Asthma than High Molecular Weight Agents?
INTRODUCTION The aim of this study was to analyse whether patients with occupational asthma (OA) caused by low molecular weight (LMW) agents differed from patients with OA caused by high molecular weight (HMW) with regard to risk factors, asthma presentation and severity, and response to various diagnostic tests. METHODS Seventy-eight patients with OA diagnosed by positive specific inhalation...
متن کاملOccupational Asthma: New Low-Molecular-Weight Causal Agents, 2000–2010
Background. More than 400 agents have been documented as causing occupational asthma (OA). The list of low-molecular-weight (LMW) agents that have been identified as potential causes of OA is constantly expanding, emphasizing the need to continually update our knowledge by reviewing the literature. Objective. The objective of this paper was to identify all new LMW agents causing occupational as...
متن کاملComparative airway response to high- versus low-molecular weight agents in occupational asthma.
Airway responses to occupational agents in sensitised workers may vary clinically and physiologically. The patterns of change in airway responsiveness, type of response and fall in expiratory flows following laboratory exposure to high- or low-molecular weight agents (HMW and LMW agents, respectively) were compared in sensitised workers. Data on workers who underwent specific inhalation challen...
متن کاملOccupational asthma due to low molecular weight agents: eosinophilic and non-eosinophilic variants.
BACKGROUND Despite having a work related deterioration in peak expiratory flow (PEF), many workers with occupational asthma show a low degree of within day diurnal variability atypical of non-occupational asthma. It was hypothesised that these workers would have a neutrophilic rather than an eosinophilic airway inflammatory response. METHODS Thirty eight consecutive workers with occupational ...
متن کاملAirway inflammation after removal from the causal agent in occupational asthma due to high and low molecular weight agents.
In order to determine 1) the features of airway inflammation after removal from exposure to high (HMW) and low (LMW) molecular weight agents 2) if there are any differences in the pattern of inflammation induced by these two types of agents, we studied 18 subjects with a recently confirmed diagnosis of occupational asthma (OA) due to HMW (n = 11) and LMW (n = 7) agents. The duration of asthma s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0156141