DNAM-1: would the real natural killer cell please stand up!
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منابع مشابه
DNAM-1: would the real natural killer cell please stand up!
Natural Killer (NK) cells were called as such due to their ability to spontaneously kill tumor cell lines in vitro. Peripheral NK cells have long been considered rapid responding innate effector lymphocyte primed to produce cytotoxic granules and pro-inflammatory cytokines such as IFN-γ and TNF-α when they encounter virusinfected, transformed or damaged self-tissue. However, it is becoming clea...
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Pleural effusions in patients with malignant disease are not invariably due to metastatic spread to the pleura and thus, they are not always incurable. For example, about 5% of patients with effusions due to lung cancer have subsequently been found to be operable and curable [1]. It is, therefore, important to assess the potential curability in all cancer patients with cytologically negative ef...
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Mitochondrial DNA sequences recovered from eight Neandertal specimens cannot be detected in either early fossil Europeans or in modern populations. This indicates that, if Neandertals made any genetic contribution at all to modern humans, it must have been limited, though the extent of the contribution cannot be resolved at present.
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Adherents of the “natural trading partner” hypothesis argue that forming a PTA is more likely to raise welfare if member countries already trade disproportionately with each other. Opponents of the hypothesis claim that the opposite is true: welfare is likely to be higher if member countries trade less with each other. This paper shows that neither analysis is correct and that the “natural trad...
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A number of competing social preference models have been developed inspired by the evidence from economic experiments. We test the relative performance of some of these models using an experimental design that is aimed at capturing pure distributional concerns in a multi-person setting. We find that the individuals in this study are heterogeneous and that they do not follow any single notion of...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2015
ISSN: 1949-2553
DOI: 10.18632/oncotarget.5952