DNAM-1 controls NK cell activation via an ITT-like motif
نویسندگان
چکیده
منابع مشابه
DNAM-1 controls NK cell activation via an ITT-like motif
DNAM-1 (CD226) is an activating receptor expressed on natural killer (NK) cells, CD8(+) T cells, and other immune cells. Upon recognition of its ligands, CD155 and CD112, DNAM-1 promotes NK cell-mediated elimination of transformed and virus-infected cells. It also has a key role in expansion and maintenance of virus-specific memory NK cells. Herein, the mechanism by which DNAM-1 controls NK cel...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2015
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.20150792