منابع مشابه
New Kid on the Block
Cysteine cathepsins are a group of proteases involved in many physiological and pathological processes. Yet, the selective detection and inhibition of individual cathepsins is still challenging. This editorial is discussing the context of a recent work introducing a designed ankyrin repeat protein (DARPin) as novel approach for selective targeting of the protease cathepsin B.
متن کاملNew kid on the block.
As Editor of the Journal of Clinical Investigation, I am pleased to announce the January 2016 launch of JCI Insight, which will publish well-executed, high-quality research across biomedicine that presents a focused yet insightful line of investigation. The new journal, published under an open-access model, represents an expansion of the American Society for Clinical Investigation's longstandin...
متن کاملThe New Kid on the Block
Give us 5 minutes and we will show you the best book to read today. This is it, the the new kid on the block that will be your best choice for better reading book. Your five times will not spend wasted by reading this website. You can take the book as a source to make better concept. Referring the books that can be situated with your needs is sometime difficult. But here, this is so easy. You c...
متن کاملGPR40 Modulators: New Kid on the Block
I mpairments in insulin secretion and action are the pathophysiological hallmarks of type 2 diabetes (1,2). Pharmacological approaches to restore b-cell function have led to the use of insulin secretagogues that include sulphonylur-eas, glinides, and glucagon-like peptide-1–based therapies. Of these, the latter hold particular clinical advantage because glucagon-like peptide-1–modulated insulin...
متن کاملA new kid on the block.
The adult heart enlarges and increases in weight in response to ischemic stress and hypertension, a process termed cardiac hypertrophy. However, the heart also increases in size after regular physiological exercise. Cardiac hypertrophy is recognized as an important process in the development of heart failure. Initial results pointed to a clear signaling pattern of physiological hypertrophy afte...
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ژورنال
عنوان ژورنال: Blood
سال: 2017
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2017-01-761635