DNA Relatedness, Phenotypic Characteristics, and Antimicrobial Susceptibilities of Globicatella sanguinis Strains

DNA relatedness, phenotypic characteristics, and antimicrobial susceptibilities of Globicatella sanguinis strains.

DNA-DNA reassociation was performed on 15 strains of Globicatella sanguinis to compare their taxonomic status with phenotypic characterization. All 15 strains selected for DNA-DNA reassociation readily met the criteria for species relatedness. The relative binding ratio was 81% or greater at the optimal temperature and 76% or greater at the stringent temperature, and the divergence was less tha...

Globicatella sanguinis meningitis associated with human carriage.

Globicatella sanguinis is a rare cause of acute meningitis. We demonstrated human carriage of Globicatella by identifying cefotaxime-resistant strains in groin and rectal specimens 9 months after invasive infection. The pathogenic strain isolated from the cerebrospinal fluid and the carriage strains were accurately identified by sodA gene sequence analysis.

Isolation of globicatella sanguinis from cerebrospinal fluid of a neonate

Meningoencephalitis associated with Globicatella sanguinis infection in lambs.

Thirty lambs displayed symptoms of meningoencephalitis. An unusual gram-positive coccus was isolated in pure culture from the blood and brain samples from one of the affected animals, and phenotypic and phylogenetic characterization showed this to be Globicatella sanguinis. This is the first report of the isolation of G. sanguinis in pure culture from an animal infection.

Infective endocarditis following urinary tract infection caused by Globicatella sanguinis

We report the first case of infective endocarditis following urinary tract infection (UTI) caused by Globicatella sanguinis in an 87-year-old Japanese woman with recurrent episodes of UTI. We identified the pathogen using the Rapid ID32 Strep system. Accurate identification of this infection is important and essential for the effective antimicrobial coverage to this pathogen.