DNA-Protein Cooperative Binding through Variable-Range Elastic Coupling
نویسندگان
چکیده
منابع مشابه
DNA-Protein Cooperative Binding through Long-Range Elastic Coupling
Cooperativity plays an important role in the action of proteins bound to DNA. A simple, mechanical mechanism for cooperativity, in the form of a tension-mediated interaction between proteins bound to DNA at two different locations, is proposed. These proteins are not in direct physical contact. DNA segments intercalating bound proteins are modeled as a Worm-Like Chain, which is free to deform i...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1999
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(99)77334-0