منابع مشابه
DNA Microarrays in Herbal Drug Research
Natural products are gaining increased applications in drug discovery and development. Being chemically diverse they are able to modulate several targets simultaneously in a complex system. Analysis of gene expression becomes necessary for better understanding of molecular mechanisms. Conventional strategies for expression profiling are optimized for single gene analysis. DNA microarrays serve ...
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The profiling of gene expression patterns with DNA microarrays is recently being widely used not only in basic molecular biological studies but also in the practical fields. In clinical application, for example, this technique is expected to be quite useful in making a correct diagnosis. In the pharmacological area, the microarray analysis can be applied to drug discovery and individualized dru...
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a long-lasting problem in the analysis of tissue samples is the time-consuming and repetitive process of histologic preparation and pathologic review of tissue sections. these two critical factors, innate nonuniformity in preparation and subjectivity of analysis, therefore limit the scientific and statistical thoroughness of tissue based studies. employing tissue microarray (tma) technique prov...
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There is a great demand for herbal medicines in the developed and developing countries because of their wide biological activity, higher safety margin than synthetic drugs as a result of this Herbal drugs have a great potential in the global market. Herbal drug technology is used for converting botanicals materials into medicines, where standardization and quality control with proper integratio...
متن کاملDNA Microarrays and Computational Analysis of DNA Microarray Data in Cancer Research
1. Introduction 2. Applications of microarrays 3. Analysis of gene expression microarrays a. Data normalization b. Detecting differentially expressed genes across different experimental conditions c. Identifying clusters of co-expressed genes i. Overview of clustering approaches ii. Assessing statistical significance of observed patterns d. Gene expression based tumor classification i. Reducing...
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ژورنال
عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine
سال: 2006
ISSN: 1741-427X,1741-4288
DOI: 10.1093/ecam/nel075