DNA Helix
نویسندگان
چکیده
منابع مشابه
NikR is a ribbon-helix-helix DNA-binding protein.
Escherichia coli NikR, a repressor with homologs in other bacteria and archaea, was identified as a potential new member of the ribbon-helix-helix (beta-alpha-alpha) family of transcription factors in profile based sequence searches and in structure prediction experiments. Biophysical and biochemical characterization of the N-terminal domain of NikR show that it has many features expected of a ...
متن کاملDNA Helix Turns 40 For
It is probably impossible to overestimate how much the 1953 report in Nature of the physical structure of DNA by Francis H. C. Crick and James D. Watson, and their interpretation of its structure in terms of its replicative function, means to modern biological science. Decoding the functional structure of DNA provided the cornerstone of the edifice that we call molecular biology, which has give...
متن کامل- turn - helix ; DNA - binding proteins )
The Saccharomyces cerevisiae CDC43 gene product is involved in establishing cell polarity during the cell-division cycle. When grown at restrictive temperatures, temperature-sensitive cdc43 mutants are unable to form buds and display delocalized cell-surface deposition [Adams et al., J. Cell Biol. (1990) in press]. We have isolated a cdc43-complementing plasmid from a yeast genomic-DNA library ...
متن کاملDNA recognition by proteins with the helix-turn-helix motif.
INTRODUCTION......... . ...... ................. .. ................. . .... . . ................. ......... 933 NOTIONS ABOUT RECOGNITION..... ................ . . .............. . . ..... . ......... . . ..... 934 THE HTH MOTIF... ..... ....... ................. .. . ................ .... . . .... ........... . .. . ..... .. 936 STRUCTURES.... . . . ..... .. ......... . . ................ ......
متن کاملA MODEL FOR THE BASIC HELIX- LOOPHELIX MOTIF AND ITS SEQUENCE SPECIFIC RECOGNITION OF DNA
A three dimensional model of the basic Helix-Loop-Helix motif and its sequence specific recognition of DNA is described. The basic-helix I is modeled as a continuous ?-helix because no ?-helix breaking residue is found between the basic region and the first helix. When the basic region of the two peptide monomers are aligned in the successive major groove of the cognate DNA, the hydrophobi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science
سال: 1969
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.164.3887.1537