DIVERSE STRESS TREATMENTS AND ACINETOBACTER BAUMANNII PERSISTER FORMATION

This study was aimed to investigate diverse stress treatments on Imipenem susceptible A. baumannii for persister cells formation. Isolates were assessed presence by colony forming unit counting (CFU/ml) after exposure (10 µg/ml) in and absence of acid treatment (pH 6) 0-7 hr. In- vitro activity curcumin synergize kill investigated. The frequency hicAB relEB type II toxin- antitoxin (TA) loci evaluated polymerase chain reaction. transcription level hicA relE toxin genes quantitative reverse transcriptase persistence varied between isolates across the conditions. treated gave fraction 0.07% 0.4% whereas + pH6 0.3% 0.7% initial untreated population. No significant reduction observed combination with (P value > 0.05). detected 100% 61.5% isolates, respectively. triggered gene while cells.