Diverse immune responses to HBV surface epitope variants after vaccine booster in adolescents immunized in infancy

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Humoral and cell-mediated immune responses after a booster dose of HBV vaccine in HIV-infected children, adolescents and young adults

OBJECTIVE HBV vaccine induces protective antibodies only in 23-56% of HIV-infected children. The aim of our study is to evaluate the immunologic effects of a booster dose of HBV vaccine in HIV-infected youth. DESIGN 53 young HIV-infected patients in whom HBV vaccination did not elicit protective Ab titers were enrolled. All patients were on ART with optimal immunological and viral response. ...

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Long-Term Protection against HBV Chronic Carriage of Gambian Adolescents Vaccinated in Infancy and Immune Response in HBV Booster Trial in Adolescence

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ژورنال

عنوان ژورنال: Clinical Microbiology and Infection

سال: 2019

ISSN: 1198-743X

DOI: 10.1016/j.cmi.2019.02.003