Disulfiram-induced dystonia

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Disulfiram Induced Psychosis

Disulfiram is the commonly prescribed drug for the treatment of alcohol dependence. It's major metabolite (diethyldithiocarbamate) is an inhibitor of dopamine-betahydroxylase, an enzyme that catalyzes the metabolism of dopamine to norepinephrine resulting in psychosis. We recommend that disulfiram should be used at the lowest effective dose, possibly 250 mg daily and caution should be taken whi...

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Disulfiram, a useful medication to deter the relapse of alcohol dependence, has been associated with a number of neuropsychiatric adverse effects. Disulfiram induced delirium is rare in the absence of an ongoing psychosis or a disulfiramethanol reaction. We present the case of an alcohol dependent patient who had a past history of both an alcohol-induced psychotic episode (which had resolved co...

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Cefotetan-induced disulfiram-type reactions and hypoprothrombinemia.

A double-blind, placebo-controlled study in eight healthy male volunteers was conducted to study possible disulfiram-type reactions and hypoprothrombinemia associated with cefotetan administration. Three doses of cefotetan (2 g) or of placebo were administered at 12-h intervals. Ethanol (0.5 g/kg of total body weight) was ingested 1 h after the third dose. Blood ethanol, serum acetaldehyde, and...

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Peripherally induced oromandibular dystonia.

OBJECTIVES Oromandibular dystonia (OMD) is a focal dystonia manifested by involuntary muscle contractions producing repetitive, patterned mouth, jaw, and tongue movements. Dystonia is usually idiopathic (primary), but in some cases it follows peripheral injury. Peripherally induced cervical and limb dystonia is well recognised, and the aim of this study was to characterise peripherally induced ...

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Speech-induced lingual dystonia.

Federal University of São Paulo, São Paulo SP, Brazil: Department of Neurology and Neurosurgery; Interdisciplinary Clinical Neurosciences Laboratory; Department of Psychiatry. Dystonia can be classified according to its etiology as primary, dystonia-plus, secondary, heredodegenerative, and psychogenic. Pure lingual dystonia is rare but not uncommon in association with other cranial dystonia. Ho...

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ژورنال

عنوان ژورنال: Journal of the Scientific Society

سال: 2016

ISSN: 0974-5009

DOI: 10.4103/0974-5009.182603