Distribution of total phenols, flavonoids and hypericin in different plant organs of wild-growing St. John’s-wort (Hypericum perforatum L., Hypericaceae) from North Macedonia
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چکیده
منابع مشابه
Factors affecting polyphenol biosynthesis in wild and field grown St. John's Wort (Hypericum perforatum L. Hypericaceae/Guttiferae).
The increasing diffusion of herbal products is posing new questions: why are products so often different in their composition and efficacy? Which approach is more suitable to increase the biochemical productivity of medicinal plants with large-scale, low-cost solutions? Can the phytochemical profile of a medicinal plant be modulated in order to increase the accumulation of its most valuable con...
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Hypericin, an extract from St John's Wort (Hypericum perforatum L.), is a promising photosensitizer in the context of clinical photodynamic therapy due to its excellent photosensitizing properties and tumoritropic characteristics. Hypericin-PDT induced cytotoxicity elicits tumor cell death by various mechanisms including apoptosis, necrosis and autophagy-related cell death. However, limited rep...
متن کاملMolecular and biochemical characterization of an enzyme responsible for the formation of hypericin in St. John's wort (Hypericum perforatum L.).
A major gene termed Hyp-1 encoding for hypericin (HyH) biosynthesis was cloned and characterized from Hypericum perforatum (St. John's wort) cell cultures. H. perforatum leaves are widely used as an herbal remedy in the treatment of mild to moderate depression. Hypericin, a photosensitive and red-colored naphthodianthrone, has been reported as the bioactive compound responsible for reversing th...
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The essential oils obtained by hydrodistillation from the aerial parts of Hypericum perforatum L. and Hypericum scabrum L. from plants growing wild in Tajikistan were analyzed by GC-MS. Sixty-six compounds were identified in the essential oils of H. perforatum with germacrene D (13.7%), α-pinene (5.1%), (E)-caryophyllene (4.7%), n-dodecanol (4.5%), caryophyllene oxide (4.2%), bicyclogermacrene ...
متن کاملImprovement of Hypericin and Hyperforin Production Using Zinc and Iron Nano-oxides as Elicitors in Cell Suspension Culture of St John's wort (Hypericum perforatum L.)
Zinc and iron nano-oxides (100 ppb) were promoted the hypericin and hyperforin production in Hypericum perforatum cell suspension culture. High performance liquid chromatography method was used for detectection and identification of hypericin and hyperforin in H. perfuratum cell suspension cultures elicited with different concentrations of zinc and iron nano-oxide (0, 50, 100 and 150 ppb) after...
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ژورنال
عنوان ژورنال: Macedonian Pharmaceutical Bulletin
سال: 2019
ISSN: 1857-8969,1409-8695
DOI: 10.33320/maced.pharm.bull.2019.65.02.005