Distribution of erm genes among Staphylococcus aureus isolates with inducible resistance to clindamycin in Isfahan, Iran

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Inducible clindamycin resistance in clinical isolates of Staphylococcus aureus due to erm genes, Iran

BACKGROUND AND OBJECTIVES Resistance to macrolide can be mediated by erm and msrA genes in Staphylococcus aureus. There are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. The aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msrA genes among S. aureus isolates. M...

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inducible clindamycin resistance in clinical isolates of staphylococcus aureus due to erm genes, iran.

background and objectives: resistance to macrolide can be mediated by erm and msra genes in staphylococcus aureus . there are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. the aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msr a genes among s. aureus isolates. ...

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Inducible clindamycin resistance among Staphylococcus aureus isolates

Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...

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Distribution of erm genes and low prevalence of inducible resistance to clindamycin among staphylococci isolates.

INTRODUCTION Resistance to macrolides, lincosamides and streptogramins B (MLS(B) antibiotics) in staphylococci may be due to modification in ribosomal target methylase encoded by erm genes. The expression of MLS(B) resistance lead to three phenotypes, namely constitutive resistance (cMLS(B)), inducible resistance (iMLS(B)), and resistance only to macrolides and streptogramins B (MS(B)). The iML...

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Inducible clindamycin resistance in clinical isolates of Staphylococcus aureus.

Background: Staphylococcus aureus is one of the most important agents causing nosocomial infections. Inducible clindamycin resistance is an important concern, because common laboratory tests could not detect it. Objectives: The aim of this study was to detect the inducible clindamycin resistance by D-test method. Materials and Methods: A total of 209 clinical S. aureus isolates were collected a...

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ژورنال

عنوان ژورنال: Advanced Biomedical Research

سال: 2016

ISSN: 2277-9175

DOI: 10.4103/2277-9175.179184