distinct inflammasome IL-1β gene expression profile in patients with psoriatic arthritis in Basra city

نویسندگان

چکیده

Psoriatic arthritis (PsA) is defined as a heterogeneous inflammation correlating with psoriasis, usually sero-negative inflammatory arthropathy and the factor genes essential for its expression prediction. Therefore, current study aimed to determination whether IL-1β gene has role in development of psoriatic arthritis. A total (128) individual participated this study, (59) (29) others arthritis, addition (40) healthy subjects. All participants were from those who attended Al-Sadr Teaching Hospital or Al-Basra teaching hospital Basra governorate, southern Iraq, August 2020 February 2022. After samples collected, peripheral blood was isolated RNA extracted estimate interest using q RT-PCR. Our results confirmed that level PsA patients up-regulated by 22.09-fold compared down-regulated psoriasis 2.8. Thus, we concluded significant

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ژورنال

عنوان ژورنال: International Journal of Health Sciences (IJHS)

سال: 2022

ISSN: ['2550-6978', '2550-696X']

DOI: https://doi.org/10.53730/ijhs.v6ns4.9122