Disseminated neonatal herpes simplex virus infection with necrotizing encephalitis: an autopsy case

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Disseminated neonatal herpes simplex virus infection with necrotizing encephalitis--an autopsy case.

An autopsy case of disseminated HSV type 2 infection occurring in a neonate at 32 weeks' gestation, delivered by cesarean section after premature rupture of membrane of 7 days duration, is presented. Herpes simplex virus type 2 was isolated from the vesicular skin lesion. The mother and patient had specific antibody to type 2 herpes simplex virus. Patient's parents had denied any herpetic orola...

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Neonatal herpes simplex virus-2 encephalitis.

Of the two virologically distinct types of Herpes simplex viruses i.e., types 1 and 2, Herpes simplex virus-2 [HSV-2] is the predominant cause of neonatal disease, and is almost always acquired from an infected maternal genital tract. Perinatally transmitted HSV-2 infection in the neonate may have either a localized, disseminated or encephalitic pattern of presentation. The encephalitic from of...

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Neonatal herpes simplex virus infection

Neonatal herpes simplex virus (HSV) infections may be caused by either herpes simplex virus type-1 (HSV-1) or herpes simplex virus type-2 (HSV-2). In the United States, HSV-2 is responsible for 75% of genital and neonatal infections, while HSV-1 causes the rest. HSV-1 more commonly affects the oropharynx, the eyes and the central nervous system.1,2 It is estimated that 20 to 30% of sexually act...

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Herpes simplex virus encephalitis.

Introduction Herpes simplex virus encephalitis is one of the more common sporadic viral encephalitides with an estimated incidence of one case per half million individuals per year (1, 2), but the true incidence may be higher. Untreated it is associated with a mortality rate exceeding 70070 and a high morbidity amongst the survivors with only about 9070 returning to normal neurological function...

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Relapse of neonatal herpes simplex virus infection.

BACKGROUND Neonatal herpes simplex virus (HSV) infection is a severe disease with high mortality and morbidity. Recurrence of skin vesicles is common. OBJECTIVE To determine the features of relapse and identify the factors related to relapse. DESIGN Thirty two surviving patients with neonatal herpes virus infections were enrolled. All patients received acyclovir treatment. Clinical and viro...

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 1987

ISSN: 1011-8934,1598-6357

DOI: 10.3346/jkms.1987.2.2.123