Disseminated histoplasmosis – Endoscopic presentation

Rare Presentation of Disseminated Histoplasmosis in an Immunocompetent Host

A 40-year-old gentleman from West Bengal, who is a farmer by profession, presented with easy fatigability, significant loss of weight, and asymptomatic, progressive nodulo-ulcerative lesions on his groins of 1 year duration. He gave no history of exploring caves or exposure to any large areas contaminated with bird droppings. General examination revealed firm, nontender, discrete cervical, axil...

A necrotic tonsillar lesion: An unusual presentation of disseminated histoplasmosis

We report a case of tonsillar histoplasmosis with hematogenous dissemination in a woman receiving infliximab for Crohn's disease. She also had a history of sarcoidosis. Due to the unusual location and confounding medical history, our case provided a diagnostic dilemma. Histoplasma infection was confirmed histologically, and the patient responded well to appropriate treatment.

Disseminated CNS histoplasmosis.

Although an estimated 40 million Americans have been infected with Histoplasma capsulatum [1], CNS involvement is rare except in the disseminated form. Lesions of the CNS have been reported to occur in nearly one fourth of the documented cases of disseminated histoplasmosis [2], but only in a few cases has the infection solely involved the CNS [3, 4]. This article details the cranial CT and spi...

Subdural Empyema in Disseminated Histoplasmosis

A 34-year-old man presented with two episodes of generalized tonic–clonic seizures and fever for 1 day. Two months back, he was admitted with high grade fever, productive cough, cervical lymphadenopathy, left lower lobe consolidation, and multiple skin abscesses. The pus from the abscess was drained and the abscess wall histopathology revealed intracellular oval shaped fungal organisms with nar...

Disseminated histoplasmosis and its treatment.