Dissecting the mechanism of torso receptor activation
نویسندگان
چکیده
منابع مشابه
Dissecting the mechanism of torso receptor activation
Regulated activation of receptor tyrosine kinases depends both on the presence of the receptors at the cell surface and on the availability of their ligands. In Drosophila the torso (tor) tyrosine kinase receptor is distributed along the surface of the embryo but it is only activated at the poles by a diffusible extracellular ligand generated at each pole which is trapped by the receptor, there...
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Formation of the Drosophila embryonic termini is controlled by the localized activation of the receptor tyrosine kinase Torso. Both Torso and Torso's presumed ligand, Trunk, are expressed uniformly in the early embryo. Polar activation of Torso requires Torso-like, which is expressed by follicle cells adjacent to the ends of the developing oocyte. We find that Torso expressed at high levels in ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 1998
ISSN: 0925-4773
DOI: 10.1016/s0925-4773(97)00181-0