Disruption of non-enzymatic antioxidant defense systems in the brain of rats with water-immersion restraint stress
نویسندگان
چکیده
منابع مشابه
Disruption of non-enzymatic antioxidant defense systems in the brain of rats with water-immersion restraint stress
We examined whether non-enzymatic antioxidant defense systems are disrupted in the brain of rats with water-immersion restraint stress. When rats were exposed to water-immersion restraint stress for 1.5, 3 or 6 h, the brain had decreased ascorbic acid and reduced glutathione contents and increased lipid peroxide and nitric oxide metabolites contents at 3 h and showed further changes in these co...
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The aims of this study were to determine 1) which cells are involved in stress-induced acute gastric mucosal lesion and 2) what kinds of molecular alterations are induced by stress, using immediate-early genes (IEG) as tools for detection of cellular activation. Male Wistar rats were exposed to acute water immersion-restraint stress. Protein and mRNA for IEG were detected by immunohistochemistr...
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In the brain, the heme oxygenase (HO) system has been reported to be very active and its modulation seems to play a crucial role in the pathophysiology of neurodegenerative disorders. Hemin as HO-1 inducer has been shown to attenuate neuronal injury so the goal of this study was to assess the effect of hemin therapy on the acute stress and how it would modulate neurological outcome. Thirty male...
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ژورنال
عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition
سال: 2012
ISSN: 0912-0009,1880-5086
DOI: 10.3164/jcbn.11-14