منابع مشابه
HER2 Intermediate Breast Cancers.
To the Editor: We were interested to read the article by Gilcrease et al ‘‘Even low level Her2 expression may be associated with worse outcome in node positive breast cancer’’ that discusses the significance of low but nonnegative Her2 protein levels in the prognosis of breast cancer. As the authors note, the conventional immunohistochemical scoring system for Her2 includes cases with 1+ expres...
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Breast cancer is a very heterogeneous disease, both at a molecular and a histological level. Five intrinsic subtypes were initially identified-Luminal-A, Luminal-B, HER2⁺, Triple negative/basal like (TNBC) and normal like-subsequently expanded to seven (Basal-like-1 and 2, mesenchymal, mesenchymal stem-like, luminal androgen receptor, immuno-modulatory and unstable). Although genetic and epigen...
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ژورنال
عنوان ژورنال: Current Oncology
سال: 2012
ISSN: 1718-7729
DOI: 10.3747/co.19.1037