Disaccharide intolerance

Disaccharide Intolerance in Infancy.

In 1958 Durand published an account of an infant with vomiting and diarrhoea since birth, and he demonstrated the presence of lactose in the urine. Since that time more widespread attention has been paid to sugar intolerance in infants, and an increasing number of reports on such cases have been published. A survey of the available published material suggests that two forms of this condition ex...

Specificity of the human intestinal disaccharidases and implications for hereditary disaccharide intolerance.

Synthesis of a jojoba bean disaccharide.

A synthesis of the disaccharide recently isolated from jojoba beans, 2-O-alpha-D-galactopyranosyl-D-chiro-inositol, has been achieved. The suitably protected chiro-inositol unit was prepared by an enantiospecific synthesis from L-xylose utilizing SmI2-mediated pinacol coupling as a key step.

The Parenteral Utilization of Disaccharide Sugars .i

The earlier literature on the behavior of carbohydrates introduced parenterally in the organism has been summarized by Albertoni (1914), Mendel and Mitchell (1905), Mendel and Kleiner (1912), and others. The trend of the results, which need not be repeated here, has been such as to indicate an apparent inability on the part of the animal organisms to metabolize more complex carbohydrates, such ...

Topoisomerase poisoning activity of novel disaccharide anthracyclines.

Doxorubicin and idarubicin are very effective anticancer drugs in the treatment of human hematological malignancies and solid tumors. These agents are well known topoisomerase II poisons; however, some anthracycline analogs recently have been shown to poison topoisomerase I. In the present work, we assayed novel disaccharide analogs and the parent drug, idarubicin, for their poisoning effects o...