Directional Switching Mechanism of the Bacterial Flagellar Motor
نویسندگان
چکیده
منابع مشابه
A molecular mechanism of bacterial flagellar motor switching.
The high-resolution structures of nearly all the proteins that comprise the bacterial flagellar motor switch complex have been solved; yet a clear picture of the switching mechanism has not emerged. Here, we used NMR to characterize the interaction modes and solution properties of a number of these proteins, including several soluble fragments of the flagellar motor proteins FliM and FliG, and ...
متن کاملStructure and Function of the Bi-Directional Bacterial Flagellar Motor
The bacterial flagellum is a locomotive organelle that propels the bacterial cell body in liquid environments. The flagellum is a supramolecular complex composed of about 30 different proteins and consists of at least three parts: a rotary motor, a universal joint, and a helical filament. The flagellar motor of Escherichia coli and Salmonella enterica is powered by an inward-directed electroche...
متن کاملThe switching dynamics of the bacterial flagellar motor - Supporting Information
The model for the stator-rotor interaction is discussed in the sections The stator-rotor interaction and The rotor switching dynamics of the main text. The model is based on the model of Oster and Blair and coworkers [1, 2], but extended to include the conformational transitions of the rotor protein complex. Here, we discuss aspects of the model that are not discussed in the main text. But, for...
متن کاملThe switching dynamics of the bacterial flagellar motor
Many bacteria are propelled by flagellar motors that stochastically switch between the clockwise and counterclockwise rotation direction. Although the switching dynamics is one of their most important characteristics, the mechanisms that control it are poorly understood. We present a statistical-mechanical model of the bacterial flagellar motor. At its heart is the assumption that the rotor pro...
متن کاملSwitching dynamics of the bacterial flagellar motor near zero load.
Switching dynamics of flagellar motors of Escherichia coli is commonly observed through markers attached to the flagellar filaments. To eliminate possible complications resulting from the conformational transitions of these filaments and to look at the output of motors more directly, we monitored motor rotation by attaching nanogold spheres to the hooks of cells lacking filaments. We observed e...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Computational and Structural Biotechnology Journal
سال: 2019
ISSN: 2001-0370
DOI: 10.1016/j.csbj.2019.07.020