Directed translocation of a flexible polymer through a cone-shaped nano-channel
نویسندگان
چکیده
منابع مشابه
Simulation studies of polymer translocation through a channel.
Monte Carlo simulation studies of the translocation of homopolymers of length N driven through a channel have been performed. We find that the translocation time tau depends on temperature in a nontrivial way. For temperatures below some critical temperature theta(c), tau approximately T-1.4, whereas for T>theta(c), tau increases with temperature. The low temperature results are in good agreeme...
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We consider the escape of a flexible, self-avoiding polymer chain out of a confined geometry. By means of simulations, we demonstrate that the translocation time can be described by a simple scaling law that exhibits a nonlinear dependence on the degree of polymerization and that is sensitive to the nature of the confining geometry. These results contradict earlier predictions but are in agreem...
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We investigate the dynamics of polymer translocation through a nanopore under an externally applied field using the 2D fluctuating bond model with single-segment Monte Carlo moves. We concentrate on the influence of the field strength E, length of the chain N, and length of the pore L on forced translocation. As our main result, we find a crossover scaling for the translocation time τ with the ...
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Polymer translocation is a promising strategy for the next-generation DNA sequencing technologies. The use of biological and synthetic nano-pores, however, still suffers from serious drawbacks. In particular, the width of the membrane layer can accommodate several bases at the same time, making difficult accurate sequencing applications. More recently, the use of graphene membranes has paved th...
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Polymer translocation through a nanopore in a membrane is investigated theoretically. Recent experiments on voltage-driven DNA and RNA translocations through a nanopore indicate that the size and geometry of the pore are important factors in polymer dynamics. A theoretical approach is presented which explicitly takes into account the effect of the nanopore length and diameter for polymer motion...
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ژورنال
عنوان ژورنال: The Journal of Chemical Physics
سال: 2013
ISSN: 0021-9606,1089-7690
DOI: 10.1063/1.4818419