Direct Positive Inotropic Effect of Acetylcholine on Myocardium
نویسندگان
چکیده
منابع مشابه
Direct positive inotropic effect of acetylcholine on myocardium. Evidence for multiple cholinergic receptors in the heart.
The effects of acetylcholine and nicotine on isometric tension, in the presence and absence of atropine, hexamethonium, and endogenous norepinephrine stores, were examined in isolated cat atria and papillary muscles. Acetylcholine exerted a negative inotropic effect, competitively inhibited by atropine, in atrial and papillary muscle; in higher concentrations in papillary muscles, it produced a...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1966
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.19.6.1097