Direct Inotropic Effects of Exogenous and Endogenous Urotensin-II
نویسندگان
چکیده
منابع مشابه
Direct inotropic effects of exogenous and endogenous urotensin-II: divergent actions in failing and nonfailing human myocardium.
BACKGROUND Urotensin-II (U-II) is an endogenous peptide upregulated in failing hearts. To date, insights into the myocardial actions of U-II have been obscured by its potent vasoconstrictor effects and interspecies differences in physiological responses to U-II. METHODS AND RESULTS We examined the direct effects of exogenous U-II on in vitro contractility in nonfailing and failing human myoca...
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ژورنال
عنوان ژورنال: Circulation: Heart Failure
سال: 2009
ISSN: 1941-3289,1941-3297
DOI: 10.1161/circheartfailure.107.748343