Direct determination of membrane resting potential and action potential in single myelinated nerve fibres
نویسندگان
چکیده
منابع مشابه
Measurement of the action potential of myelinated nerve fiber.
THE PEAK VALUE of the action potential of the vertebrate myelinated fiber has been previously recorded by a number of investigators. (1-5 and others). Values range from about 60-155 mv depending on the method employed. These methods may be divided into three general categories. The action potential at the node of a single fiber may be estimated from a knowledge of the action current in the axis...
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It has long been considered that anode break excitation (ABE) is not elicitable in normal isolated nerve fibres. Quite recently, one of the authors (Konishi, 1957) found that it was due to weakness of the current applied and that, if a strong current (more than ten times the rheobase) was used, a single fibre, too, gave readily ABE. The present paper deals chiefly with threshold conditions for ...
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This brief review is intended to serve as a refresher on the ideas associated with teaching students the physiological basis of the resting membrane potential. The presentation is targeted toward first-year medical students, first-year graduate students, or senior undergraduates. The emphasis is on general concepts associated with generation of the electrical potential difference that exists ac...
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23 Sound-evoked compound action potential (CAP), which captures the synchronous activation 24 of the auditory nerve fibres (ANFs), is commonly used to probe deafness in experimental and 25 clinical settings. All ANFs are believed to contribute to CAP threshold and amplitude: low 26 sound-pressure levels activate the high-spontaneous rate (SR) fibres, and increasing levels 27 gradually recruit m...
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Repetitive activity at the non-myelinated ending of Pacinian corpuscles leaves the following after-effects: (1) With certain parameters of repetitive mechanical stimulation of the ending a depression in generator potential is produced. The effect is fully reversible and has low energy requirements. The effect is a transient decrease in responsiveness of the receptor membrane which is unrelated ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1951
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1951.sp004545