Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions

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Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions

An efficient solvent-free protocol for regioselective bromination of substituted coumarins has been developed by using dioxane dibromide as the solid brominating agent. The efficacy of the solvent-free protocol has been established. The effects of the electronic nature and location of the substituents on the outcome of the reaction have been rationalized with a proposed mechanism.

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Synthesis of substituted trisphenols by use of a double acidic ionic liquid under solvent-free conditions

3-methyl-1-(4-sulfobuthyl)-1-H-imidazol-3ium hydrogen sulfate, as a dual acidic ionic liquid (DAIL), was found to be an efficient catalyst for the simple, rapid and green synthesis of substituted trisphenols from the condensation of different substituted phenols and 2,6-bis (methylol) phenols (BMP). DAIL catalyst efficiently promoted the reaction between phenols and BMPs with a variety of funct...

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Silica gel-mediated organic reactions under organic solvent-free conditions.

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ژورنال

عنوان ژورنال: Beilstein Journal of Organic Chemistry

سال: 2012

ISSN: 1860-5397

DOI: 10.3762/bjoc.8.35