Diffuse maculopapular exanthema and a positive lymphocyte transformation test reaction in response to clarithromycin
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منابع مشابه
Herbal medicine and false-positive results on lymphocyte transformation test.
In vitro mitogenic activity of 16 herbs and 3 Kampo (herbal medicine) formulae have been reported in experimental studies. It is not known how many herbs and Kampo formulae in total have mitogenic activity. Lymphocyte transformation test (LTT) is generally utilized to diagnose drug-induced liver injury. In LTT, mitogenic activity is assessed by measuring 3H-thymidine incorporation. The objectiv...
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We present the case of bronchospastic reaction to clarithromycin had during a drug challenge test. Personal allergic history was negative for respiratory allergies and positive for adverse drug reactions to general and regional anesthesia and to ceftriaxone. After the administration of 1/4 of therapeutic dose of clarithromycin the patient showed dyspnea, cough and bronchospasm in all the lung f...
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of lichen planus follicularis tumidus and Hashimoto’s thyroiditis. An Bras Dermatol. 2017;92(4):585-7. Mailing address: Hatice Kaya Ozden Kocaeli Derince Training and Research Hospital Dermatology Department 41900 Kocaeli / Turkey E-mail: [email protected] We observed a slightly itchy, tumid, violaceous plaque in our patient only in the left retroauricular region and classic lichen planus lesion...
متن کاملThe lymphocyte transformation test and gold hypersensitivity.
The Empire Rheumatism Council's controlled trial (1960) showed that gold salts benefit patients with rheumatoid arthritis. However, side-effects still occur with this treatment despite regular blood counts and urine examinations and, although the incidence of severe reactions has probably been reduced by careful attention to the dose and number of injections given, serious haematological compli...
متن کاملGenetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients
OBJECTIVE To characterize, among European and Han Chinese populations, the genetic predictors of maculopapular exanthema (MPE), a cutaneous adverse drug reaction common to antiepileptic drugs. METHODS We conducted a case-control genome-wide association study of autosomal genotypes, including Class I and II human leukocyte antigen (HLA) alleles, in 323 cases and 1,321 drug-tolerant controls fr...
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ژورنال
عنوان ژورنال: Oxford Medical Case Reports
سال: 2018
ISSN: 2053-8855
DOI: 10.1093/omcr/omy061