منابع مشابه
Diffuse Axonal Injury in Head Trauma
Background: Diffuse axonal injury (DAI) is one of the most common and important pathologic features of traumatic brain injury (TBI). The susceptibility of axons to mechanical injury appears to be due to both their viscoelastic properties and their high organization in white matter tracts. Although axons are supple under normal conditions, they become brittle when exposed to rapid deformations a...
متن کاملDiffuse axonal injury in head trauma.
Diffuse axonal injury (DAI) as defined by detailed microscopic examination was found in 34 of 80 consecutive cases of head trauma surviving for a sufficient length of time to be clinically assessed by the Royal Adelaide Hospital Neurosurgery Unit. The findings indicate that there is a spectrum of axonal injury and that one third of cases of DAI recovered sufficiently to talk between the initial...
متن کاملDiagnostic challenge of paroxysmal sympathetic hyperactivity (PSH) associated with diffuse axonal injury (DAI) in head trauma
Dear Editor it is well known that many patients show a significant altered level of consciousness after head trauma, and they subsequently present neurological sequelae, without any relevant findings in the CT scan. This is often due to the presence of diffuse axonal injury (DAI). The purpose of this study was to investigate the factors associated with DAI, especially the occurrence of paroxysm...
متن کاملA morphological study of diffuse axonal injury in a rat model by lateral head rotation trauma.
Morphology in diffuse axonal injury (DAI) by lateral head rotation was investigated. SD rats were divided into injury (n=9) and sham (n=3) groups. A device was used to produce lateral rotational acceleration of the rats' heads. At different survival times three rats were killed for light and electron microscopic examination of the brain tissue. Sagittal sections were made from medulla oblongata...
متن کاملevaluation of the effect of glibenclamide in patients with diffuse axonal injury due to moderate to severe head trauma
objectives we aim to evaluate the role of glibenclamide on the short-term outcome of patients with dai due to moderate to severe tbi. patients and methods in this controlled randomized clinical trial, 40 patients with moderate to severe tbi were assigned to glibenclamide (n = 20) and control (n = 20) groups. six hours after admission the intervention group received 1.25 mg glibenclamide every 1...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1989
ISSN: 0022-3050
DOI: 10.1136/jnnp.52.7.838