Diffuse axonal injury: diffusion tensor imaging and cognitive outcome
نویسندگان
چکیده
منابع مشابه
Diffusion tensor MR imaging in diffuse axonal injury.
BACKGROUND AND PURPOSE Disruption of the cytoskeletal network and axonal membranes characterizes diffuse axonal injury (DAI) in the first few hours after traumatic brain injury. Histologic abnormalities seen in DAI hypothetically decrease the diffusion along axons and increase the diffusion in directions perpendicular to them. DAI therefore is hypothetically associated in the short term with de...
متن کاملDiffusion tensor imaging as potential biomarker of white matter injury in diffuse axonal injury.
BACKGROUND AND PURPOSE Multiple biomarkers are used to quantify the severity of traumatic brain injury (TBI) and to predict outcome. Few are satisfactory. CT and conventional MR imaging underestimate injury and correlate poorly with outcome. New MR imaging techniques, including diffusion tensor imaging (DTI), can provide information about brain ultrastructure by quantifying isotropic and anisot...
متن کاملDiffuse axonal injury in mild traumatic brain injury: a diffusion tensor imaging study.
OBJECT Diffuse axonal injury (DAI) is a major complication of traumatic brain injury (TBI) that leads to functional and psychological deficits. Although DAI is frequently underdiagnosed by conventional imaging modalities, it can be demonstrated using diffusion tensor imaging. The aim of this study was to assess the presence and extent of DAI in patients with mild TBI. METHODS Forty-six patien...
متن کاملDiffusion tensor tractography of traumatic diffuse axonal injury.
BACKGROUND Diffuse axonal injury is a common consequence of traumatic brain injury that frequently involves the parasagittal white matter, corpus callosum, and brainstem. OBJECTIVE To examine the potential of diffusion tensor tractography in detecting diffuse axonal injury at the acute stage of injury and predicting long-term functional outcome. DESIGN Tract-derived fiber variables were ana...
متن کاملDetecting diffuse axonal injury in rat brainstems by diffusion tensor imaging and AQP4 expression.
This study investigated the correlation between AQP4 expression and DTI in rat brainstems after diffuse axonal injuries (DAI). Forty rats were imaged before injury and reimaged at 3, 6, 12, 24 and 72 h post-injury. A control group of 8 rats was imaged and sacrificed for histology but not injured. After brain injury, AQP4 expression and ADC values in the brainstems increased gradually, reaching ...
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ژورنال
عنوان ژورنال: Arquivos de Neuro-Psiquiatria
سال: 2018
ISSN: 1678-4227,0004-282X
DOI: 10.1590/0004-282x20180113