Differentiation of Uterine Natural Killer Cells in Pregnant SCID (scid/scid) Mice
نویسندگان
چکیده
منابع مشابه
Differentiation of uterine natural killer cells in pregnant SCID (scid/scid) mice.
To determine whether functional T- and B-cells can affect differentiation and/or proliferation of uterine natural killer (uNK) cells, their numbers in SCID mice (genotype, C.B.-17/Icr-scid/scid) were compared with those of control mice (genotype, C.B.-17/Icr-+/+) on days 8, 12 and 16 of pregnancy. Using biotinylated-Dolichos biflorus agglutinin (DBA) lectin staining, uNK cells can be readily cl...
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results the ovarian hormones level showed a significant difference between the experimental and control groups (p < 0.05). furthermore, the unk cell population showed a significant difference between the two groups (p < 0.05). conclusions increased ovarian hormones due to low-dose aspirin administration resulted in decline in the unk cells number, which may be effective in successful pregnancy....
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Uterine natural killer (uNK) cells remarkably increase in number after implantation. NK cells or their precursors migrate from the blood stream and contribute to the increase. However, the contribution of uNK cells present in the virgin uterus has been unclear. To elucidate this issue, we examined uterine leukocyte subsets during pregnancy in BALB/c mice. The most dramatic change was the massiv...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2011
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.11-0189